abstract：:Lupus is now regarded as a syndrome which results from several related auto-immune processes, although the exact mechanisms of how the disease arises in susceptible individuals remain obscure. When the San Carlo meetings began in 1968, much less was known about the pathogenesis of autoimmunity, but the presence of aut...

journal_title：Journal of nephrology

authors： Cameron JS

更新日期：1999-07-01 00:00:00

abstract：:The management of rapidly progressive glomerulonephritis has been transformed over the past thirty years. It has become one of the few forms of glomerulonephritis that can be effectively treated, and today overall renal survival is as high as 70%. Effective management of patients with RPGN requires prompt and accurate...

journal_title：Journal of nephrology

authors： Erwig LP,Rees AJ

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Carotid artery intima-media thickness (CIMT) has been used as a marker of atherosclerosis. An insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is associated with various cardiovascular diseases. This study is aimed at evaluating early atherosclerotic involvement of caroti...

journal_title：Journal of nephrology

authors： Nergizoğlu G,Keven K,Gürses MA,Aras O,Ertürk S,Duman N,Ateş K,Akar H,Akar N,Karatan O,Erbay B,Ertuğ AE

更新日期：1999-07-01 00:00:00

abstract：:Recently, two independent teams detected presumed hepatitis agents, which were designated HGV and hepatitis GB virus C; they represent a new genus in the family Flaviviridae. The most accurate way to assess the epidemiology of GBV-C/HGV infection remains the combination of RT-PCR and anti-GBV-C/HGV E2 techniques, to d...

journal_title：Journal of nephrology

authors： Fabrizi F,Martin P

更新日期：1999-05-01 00:00:00

abstract：:IgA nephropathy (IgAN) is characterised by the mesangial deposition of polymeric IgA1 (pIgA1). pIgA1 production is reduced in the mucosal immune system in IgAN and increased in the marrow; this switch may be secondary to a defect in gammadeltaT cell control of IgA production. However this does not explain the mechanis...

journal_title：Journal of nephrology

authors： Feehally J,Allen AC

更新日期：1999-03-01 00:00:00

abstract：:The kidney does not usually present specific lesions in cystic fibrosis (CF), although in recent years renal involvement has been reported, particularly amyloidosis and immune complex glomerulonephritis. IgA nephropathy is rare. We report four cases of IgA nephropathy out of five renal biopsies performed in the last t...

journal_title：Journal of nephrology

authors： Stirati G,Antonelli M,Fofi C,Fierimonte S,Pecci G

更新日期：1999-01-01 00:00:00

abstract：:Some antihypertensive drugs may have a renoprotective effect, that is partially independent of their ability to reduce blood pressure. ACE-inhibitors are safe and effective agents that are capable of reducing proteinuria and preventing CRF progression. The results of the AIPRI extension study suggest that they may als...

journal_title：Journal of nephrology

authors： Locatelli F,Del Vecchio L,Marai P,Colzani S

更新日期：1998-11-01 00:00:00

abstract：:We report 4 cases of sepsis-induced acute renal failure (ARF) with peculiar clinical presentation in which the renal biopsy was the only clue to a correct diagnosis. We observed 66 cases of ARF in a 4-year experience. Seven (11%) were associated with sepsis; in 3 of these (4.5%) a shock was present. Clinical picture o...

journal_title：Journal of nephrology

authors： Feriozzi S,Muda AO,Massimetti C,Costantini S,Ancarani E

更新日期：1998-09-01 00:00:00

abstract：:We describe a patient with renal transplant who developed abdominal pain and acute nephritis in the course of the follow-up. A biopsy of colon lesions revealed CMV inclusions, renal biopsy revealed acute glomerulonephritis with positive CMV-DNA on polymerase chain reaction. The renal disease and bowel symptoms complet...

journal_title：Journal of nephrology

authors： Gotti E,Abbate M,Ferrante P,Remuzzi G

更新日期：1998-07-01 00:00:00

abstract：:With increasingly accurate non-invasive tests, the clinician frequently discovers obstruction of the renal arteries by atherosclerosis. The decision to reverse this obstruction is not straightforward, particularly when blood pressure can be easily controlled with medications. Proper management of this problem requires...

journal_title：Journal of nephrology

authors： Middleton JP

更新日期：1998-05-01 00:00:00

abstract：:Highly concentrated marine polyunsaturated fatty acids (n-3 PUFA), affecting the lipids and lipophilic drugs metabolism, can interfere with cyclosporine (CyA) pharmacokinetics. This prospective, randomized and placebo-controlled, double-blind study involved 42 kidney graft recipients. From day +1, 21 pts (E) received ...

journal_title：Journal of nephrology

authors： Busnach G,Stragliotto E,Minetti E,Perego A,Brando B,Broggi ML,Civati G

更新日期：1998-03-01 00:00:00

abstract：:Preemptive isolated liver transplantation (PLTX) can cure the metabolic defect in primary hyperoxaluria type 1 (PH1) but there are no uniformally accepted recommendations concerning the timing of this transplantation procedure. We have performed PLTX successfully in 4 children (age 3-9 years) with PH1 with no mortalit...

journal_title：Journal of nephrology

authors： Kemper MJ,Nolkemper D,Rogiers X,Timmermann K,Sturm E,Malago M,Broelsch CE,Burdelski M,Müller-Wiefel DE

更新日期：1998-03-01 00:00:00

abstract：:There is little doubt that molecular biological intervention therapy has come of age and its potential is arousing tremendous excitement. A gene transfer technique, the HVJ-liposome method, is now applicable as a tool for the dissection of molecular aspects in the pathophysiology of renal diseases, and for gene therap...

journal_title：Journal of nephrology

authors： Imai E,Isaka Y,Akagi Y,Kaneda Y,Hori M

更新日期：1998-01-01 00:00:00

abstract：:Some patients with essential hypertension manifest increased urinary albumin excretion (UAE). Hypertensive patients with microalbuminuria manifest abnormal circadian variation of blood pressure, increased serum levels of LDL-cholesterol and lipoprotein(a), a greater rise of serum insulin in response to an oral glucose...

journal_title：Journal of nephrology

authors： Bianchi S,Bigazzi R,Campese VM

更新日期：1997-07-01 00:00:00

abstract：:The newly described endothelium-dependent vasoactive substances, nitric oxide and endothelins, have been the subject of intense investigative interest and have been demonstrated to promote a wide array of autocrine and paracrine functions. Recent data highlight their emerging role as potential important mediators of r...

journal_title：Journal of nephrology

authors： Epstein M,Goligorsky MS

更新日期：1997-05-01 00:00:00

abstract：:Cyclosporine A has been empirically used for more than 12 years in the treatment of idiopathic nephrotic syndrome, in both children and adults. There is consistent evidence, from both experimental and human studies, that the highly lipophilic cyclosporine molecule diminishes or abolishes proteinuria by two differing m...

journal_title：Journal of nephrology

authors： Meyrier A

更新日期：1997-01-01 00:00:00